one flushing, taking on time,
using cup, accurate quantity.
it features large dispersion of particles, high bioavailability and long action time.
Strong sustained release effect
a large number of documents have proved that the sustained release effect of this drugs is more obvious.
Easy to absorb
oral taking is convenient, there is no
tablet disintegration problem, especially suitable for patients with dysphagia masticatory and dysphagia.
designed for children, it is the most popular among children,
with good tolerance.
Product Center > Amoxicillin and Clavulanate Potassium Dry Suspension
【Ingredients】This product is a compound preparation and its components are as follows:
1.Each bottle contains Amoxicillin (C16H19N305S) 2.0g and Clavulanate Potassium
（C8H9NO5）0.285g. 50ml suspension is prepared with water before use.
2.Each bottle contains Amoxicillin (C16H19N305S) 4.0g and Clavulanate Potassium
(C8H9NO5) 0.57g. 50ml suspension is prepared with water before use.
【Suitability】This product is used to treat infections caused by sensitive strains of
microorganisms specified in the following conditions:
1. Lower respiratory tract infection: caused by Hemophilus or
Moraxella produced from β-lactamases.
2. Otitis media: caused by Hemophilus or Moraxella produced from β-lactamases.
3. Nasosinusitis: caused by Hemophilus or Moraxella produced from β-lactamases.
4. Skin and soft tissue infection: caused by Staphylococcus, Escherichia coli or Klebsiella
produced from β-lactamases.
5. Urinary tract infection: caused by Escherichia coli, Klebsiella or Enterobacteriaceae.
6. Lower inspiratory trait infection: caused by Hemophilus or Moraxella produced from β-lactamases.
Although this product is effective for all kinds of infections mentioned above, the infection caused by bacteria sensitive to Ampicillin can also be treated
with this product because it contains Amoxicillin.Therefore, the complex infection caused by microorganisms sensitive to Ampicillin and microorganisms
producing β-lactamase is sensitive to this product and there is no need for other antibiotics.Because Amoxicillin is more effective against Streptococcus
Genicularis in vitro than Ampicillin and Penicillin, Therefore, most of Streptococcus Pneumoniae which are neutral sensitive to Ampicillin or Penicillin are
completely sensitive to Amoxicillin. Bacteriological tests shall be carried out with surgery in order to detect pathogenic bacteria and their sensitivity to this
product.When infection may involve the above-mentioned microorganisms that produce β-lactamases. Treatment should be started before bacteriological
and sensitivity tests are obtained in order to detect pathogenic bacteria and their sensitivity to this product. Once the results are known, the treatment plan
should be adjusted in a timely manner.
use only biological enzyme agents to reduce toxic emissions
no toxic chemical solvent is added, the residual impurity is less,
and the incidence of allergy is low
the secondary crystal is bigger
and more stable,
which is more convenient for preservation.
The content of the products of the same specification is 2% higher than that of the chemical products,
and the curative effect is more accurate.
The duration of antibiotic concentration in plasma exceeding MIC (T > MIC) is an important parameter to evaluate the curative effect.
In the study of the inhibitory effect of different dosage regimens on Hemophilus Influenzae,
Amoxicillin t > MIC could achieve the best curative effect 164 at 40%, Cmax/MIC, reflected the peak value of Amoxicillin in simulated plasma at 7: 1 showed antibacterial concentration is higher, that is to say, the ratio is the best.
Taking a Lead
in Consistency Evaluation
The evaluation process of generic drug consistency in Amoxicillin and Clavulanate Potassium Dry
Suspension saves the cost of time and cost technical evaluation, and the risk of non-reference preparation.
The number of competing brands in market of the same variety is reduced, and meanwhile the drugs through consistency evaluation
will gradually stand firm in the market and win an absolute dominant position.
The drugs that fails to pass the consistency evaluation will be eliminated out. The advantage of drug bidding group:
the generic drugs that pass the quality consistency evaluation will have obvious advantages in the bidding rules.
Amoxicillin and Clavulanate Potassium
Dry Suspension Standard Preparation:
originally developed product by GSK,
Amoxicillin and Clavulanate Potassium Dry
Suspension (Bottled preparation,
with Ratio of 7:1)
Lean & Leap
Amoxicillin and Clavulanate Potassium
(Bottled preparation with Ratio of 7:1 )
Other Amoxicillin and Clavulanate Potassium Dry Suspension
preparation is all of bag package with various Ratios. (4:1;7:1;14:1, etc.)
Lean & Leap Akegan suspension is the only product in the market with standard reference preparations
Lean & Leap Will lead the consistency evaluation of Akegan suspension,
other bag packaging is difficult to pass the consistency evaluation work
Treatment Group: the treatment group was treated with Amoxicillin and Clavulanate Potassium (7:1) Dry Suspension twice a day.
Control group: the control group was given Amoxicillin Granule Tablets, 50~100mg/kg per day, divided into 3~4 times,
consecutive use for 4 ~ 10 days according to the actual condition.
Amoxicillin Clavulanate Potassium (7: 1) Dry Suspension was produced by enzyme method without organic solvent pollution.
the treatment effect on the children infected is ideal, and is also safe in the treatment dose; At the same time, it has good tolerance, easy to take twice a day,
orange taste not only increases the adaptability of children, but also improves compliance, and the side effects of diarrhea are significantly reduced.
Therefore, the importance of this product in the treatment of infantile bronchitis will be continuously increased.
Advantage of Drug Form